Potassium Cation → Methyl 3-(5'-fluoro-2,2-dimethyl-2'-oxospiro[cyclopropane-1,3'-indole]-1'-yl)-5-(2-oxo-1,3-oxazolidin-3-yl)benzoate

HRID 205936Notes

Reaction equation

HRID 205936 reaction equation
[C:33](=[O:34])([O-:35])[O-:36].[CH3:16][O:17][C:18]([c:19]1[cH:20][c:21]([Br:31])[cH:22][c:23]([N:25]2[C:26](=[O:30])[O:27][CH2:28][CH2:29]2)[cH:24]1)=[O:32].[CH3:39][NH:40][CH2:41][CH2:42][NH:43][CH3:44].[CH3:45][C:46]#[N:47].[Cu:48][I:49].[F:1][c:2]1[cH:3][c:4]2[c:5]([cH:6][cH:7]1)[NH:8][C:9](=[O:15])[C:10]21[C:11]([CH3:13])([CH3:14])[CH2:12]1.[K+:37].[K+:38]>>[F:1][c:2]1[cH:3][c:4]2[c:5]([cH:6][cH:7]1)[N:8]([c:21]1[cH:20][c:19]([C:18]([O:17][CH3:16])=[O:32])[cH:24][c:23]([N:25]3[C:26](=[O:30])[O:27][CH2:28][CH2:29]3)[cH:22]1)[C:9](=[O:15])[C:10]21[C:11]([CH3:13])([CH3:14])[CH2:12]1

Participants

8

Reactant 7

HCID 813Potassium Cation2×HCID 6342AcetonitrileHCID 8070N,N'-DimethylethylenediamineHCID 19660Carbonate IonHCID 24350Copper(1+) iodide; Copper(I) iodide; Cuprous iodide; Cuprous iodide (CuI)HCID 67229228Methyl-3-bromo-5-(2-oxooxazolidin-3-yl)benzoateHCID 772517685-fluoro-2',2'-dimethylspiro[1H-indole-3,1'-cyclopropane]-2-one

Product 1

HCID 58305283Methyl 3-(5'-fluoro-2,2-dimethyl-2'-oxospiro[cyclopropane-1,3'-indole]-1'-yl)-5-(2-oxo-1,3-oxazolidin-3-yl)benzoate

Sources & evidence

ORD record
ord-fee67954143b4c5fab1fc4c8eb33e644
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (6/10)

Reaction notes

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