反应详情

温度

100 °C

A mixture of 3-{4-[(2E)-3-(dimethylamino)prop-2-enoyl]phenoxy}-5-[(1S)-2-methoxy-1-methylethoxy]-N-(1-methyl-1H-pyrazol-3-yl)benzamide (100 mg, 0.209 mmol) and hydrazine hydrate (0.204 mL, 4.18 mmol) in ethanol (3 mL) was heated to 100° C. for 5 minutes in a ‘Smith Creator’ microwave. The volatiles were removed in vacuo to give the product as a colourless foam (92 mg).

1. customThe volatiles were removed in vacuo