HCID 67542813, compound → HCID 25260754, compound

Participants

Reaction Steps

3.2 120 mg of tert-butyl N′-{2-[3-(2,6-dichlorophenylamino)imidazo[1,2-a]-pyrimidin-2-yl]-3,5-dimethoxybenzoyl}hydrazinecarboxylate are stirred at RT for 1 hour in 3 ml of 4 N HCl in dioxane. The reaction mixture is evaporated, the residue is triturated with a little ethyl acetate and filtered off with suction, giving 90 mg (84%) of 2-[3-(2,6-dichlorophenylamino)imidazo-[1,2-a]pyrimidin-2-yl]-3,5-dimethoxybenzohydrazide as hydrochloride; MS-FAB (M+H+)=474.3; Rf (polar method): 1.33 min.

Provenance & Evidence