反应详情

温度

25 °C

Trifluoroacetic acid (13 eq) was added dropwise to a solution of tert-butyl 2-(2-(N-cyclopropyl-4-methoxy-2,6-dimethylphenylsulfonamido)ethoxy)acetate in dichloromethane (10 ml/mmol) at 0° C. and the resulting solution was stirred for 2 h at 25° C. The mixture was concentrated completely and traces of trifluoroacetic acid removed under high vacuum. The crude product was used directly in the next stage with no further processing.

1. concentrationThe mixture was concentrated completely
2. customremoved under high vacuum