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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2059907Generated: October 29, 2026

1-(8-Phenyl-1,4-dioxaspiro[4.5]decan-8-yl)pyrrolidine → 4-Phenyl-4-(1-pyrrolidinyl)cyclohexanone

https://huagongshe.com/reaction/2059907

Reaction equation

Participants

RoleNameHCIDCharge
Reactant1-(8-Phenyl-1,4-dioxaspiro[4.5]decan-8-yl)pyrrolidineHCID 13345264—
ReactantHCID 59311794HCID 59311794—
Product4-Phenyl-4-(1-pyrrolidinyl)cyclohexanoneHCID 1334527280%

Reaction Steps

The reaction was performed starting from 1-(8-phenyl-1,4-dioxaspiro[4.5]decan-8-yl)pyrrolidine in an analogous manner to stage 2 amine (A1). Yield: 80%

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08278319B2
Source datasetuspto-grants-2012_10
ORD IDord-bf402fceb8c443f297a0d3d8605fae96
Source noteuspto-grants-2012_10