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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2059910Generated: October 30, 2026

8-(3-fluorophenyl)-N,N-dimethyl-1,4-dioxaspiro[4.5]decan-8-amine → 4-(Dimethylamino)-4-(3-fluorophenyl)cyclohexan-1-one

https://huagongshe.com/reaction/2059910

Reaction equation

Participants

RoleNameHCIDCharge
Reactant8-(3-fluorophenyl)-N,N-dimethyl-1,4-dioxaspiro[4.5]decan-8-amineHCID 57475110—
ReactantHCID 59311794HCID 59311794—
Product4-(Dimethylamino)-4-(3-fluorophenyl)cyclohexan-1-oneHCID 57475111—

Reaction Steps

The reaction was performed starting from 8-(3-fluorophenyl)-N,N-dimethyl-1,4-dioxaspiro[4.5]decan-8-amine in an analogous manner to stage 2 amine (A1).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08278319B2
Source datasetuspto-grants-2012_10
ORD IDord-145a57f1a8174b2683aed84a8b09cf43
Source noteuspto-grants-2012_10