Ethyl formate → HCID 59370483, compound

Participants

Reaction Steps

{2-[2-Methyl-3-(methyloxy)phenyl]ethyl}amine (Preparation 10; 1.75 g; 10.6 mmol) was heated under reflux with ethyl formate (97%; 15 ml) for 15 h. Removal of the solvent gave the crude product (ca. 2 g), which was purified by chromatography on silica gel, eluting with a gradient of 13-63% ethyl acetate in cyclohexane, to give the title compound (1.57 g).

Provenance & Evidence