Ammonia → 2-(difluoromethyl)-4-methoxy-1-[4-(4-morpholinyl)-6-(1-piperazinyl)-1,3,5-triazin-2-yl]-1H-benzimidazole
Reaction equation
[Cl:48][CH2:49][Cl:50].[F:1][CH:2]([c:3]1[n:4][c:5]2[c:6]([n:7]1-[c:8]1[n:9][c:10]([N:20]3[CH2:21][CH2:22][N:23]([C:26]([O:27][C:28]([CH3:29])([CH3:30])[CH3:31])=[O:32])[CH2:24][CH2:25]3)[n:11][c:12]([N:14]3[CH2:15][CH2:16][O:17][CH2:18][CH2:19]3)[n:13]1)[cH:33][cH:34][cH:35][c:36]2[O:37][CH3:38])[F:39].[F:40][C:41]([F:42])([F:43])[C:44]([OH:45])=[O:46].[NH3:47]>>[F:1][CH:2]([c:3]1[n:4][c:5]2[c:6]([n:7]1-[c:8]1[n:9][c:10]([N:20]3[CH2:21][CH2:22][NH:23][CH2:24][CH2:25]3)[n:11][c:12]([N:14]3[CH2:15][CH2:16][O:17][CH2:18][CH2:19]3)[n:13]1)[cH:33][cH:34][cH:35][c:36]2[O:37][CH3:38])[F:39]Participants
5
Reactant 4
Product 1
Sources & evidence
- ORD record
- ord-1c0ccef8dccc413b99a7304cf76215e6
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (6/10)
Reaction notes
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