反应详情

0.69 g of 5% palladium on activated carbon was added, under a nitrogen atmosphere, to 15 g of 3-(trifluoromethoxy)-cinnamic acid in about 125 ml of ethyl acetate p.a., and hydrogenation was then carried out for 18 hours at room temperature under a hydrogen pressure of 2 bar. Filtration over kieselguhr was then carried out, followed by washing three times with ethyl acetate, and the combined filtrates were concentrated in vacuo at from 25 to 40° C. (yield 15.8 g).

1. filtrationFiltration over kieselguhr
2. washby washing three times with ethyl acetate
3. concentrationthe combined filtrates were concentrated in vacuo at from 25 to 40° C. (yield 15.8 g)