反应详情

14 g of the product from step 3 were dissolved in water; the solution was adjusted to pH 12 with 32% sodium hydroxide solution, while cooling with ice, and extracted three times with dichloromethane, and the combined organic phases were dried over magnesium sulfate, filtered and concentrated in vacuo.

1. temperaturewhile cooling with ice
2. extractionextracted three times with dichloromethane
3. dry with materialthe combined organic phases were dried over magnesium sulfate
4. filtrationfiltered
5. concentrationconcentrated in vacuo