HuagongsheHuagongshe Chemistry Print Report · For research reference only
4-Fluorobenzoyl chloride → 1-(4-Fluoro-benzoyl)-pyrrolidine-3-carboxylic acid ethyl ester
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 4-Fluorobenzoyl chloride | HCID 67879 | — |
| Reactant | Ethyl pyrrolidine-3-carboxylate | HCID 12896002 | — |
| Product | 1-(4-Fluoro-benzoyl)-pyrrolidine-3-carboxylic acid ethyl ester | HCID 59322225 | 76% |
Reaction Steps
The title compound was prepared according to the method described for Preparation 2 using pyrrolidine-3-carboxylic acid ethyl ester (see Preparation 1) and 4-fluoro-benzoyl chloride to afford the title compound as a colourless oil (4.3 g, 76%).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08278343B2 |
| Source dataset | uspto-grants-2012_10 |
| ORD ID | ord-9b6598db7363478d85e9bd0569732f71 |
| Source note | uspto-grants-2012_10 |