HuagongsheHuagongshe Chemistry Print Report · For research reference only
4-Hydroxyphenylboronic acid → 6-(4-Hydroxyphenyl)nicotinonitrile
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 4-Hydroxyphenylboronic acid | HCID 2734360 | — |
| Reactant | 6-Bromopyridine-3-carbonitrile | HCID 5005718 | — |
| Product | 6-(4-Hydroxyphenyl)nicotinonitrile | HCID 135753378 | 23% |
Reaction Steps
The title compound was prepared according to the method described for Preparation 17 using 4-hydroxybenzene boronic acid and 2-bromo-5-cyanopyridine to afford the title compound as a white solid (250 mg, 23%)
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08278343B2 |
| Source dataset | uspto-grants-2012_10 |
| ORD ID | ord-3b9ccf186e6b40b5bd8715a7d18adda7 |
| Source note | uspto-grants-2012_10 |