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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2060244Generated: October 30, 2026

2,5-Dichloropyrimidine → 4-(5-Chloropyrimidin-2-yl)phenol

https://huagongshe.com/reaction/2060244

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2,5-DichloropyrimidineHCID 590641—
Reactant4-Hydroxyphenylboronic acidHCID 2734360—
Product4-(5-Chloropyrimidin-2-yl)phenolHCID 13605258229%

Reaction Steps

The title compound was prepared according to the method described for Preparation 17 using 4-hydroxybenzene boronic acid and 2,5-dichloro-pyrimidine to afford the title compound as a pale yellow solid (1.91 g, 29%)

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08278343B2
Source datasetuspto-grants-2012_10
ORD IDord-12d4b1e1afe441e9a55120ad26a9d100
Source noteuspto-grants-2012_10