Glycinamide → HCID 178516758, compound

HRID 2060251Notes

Reaction equation

HRID 2060251 reaction equation
[F:1][C:2]1[CH:7]=[CH:6][C:5]([C:8](=O)[CH:9]=O)=[CH:4][CH:3]=1.[NH2:12][CH2:13][C:14]([NH2:16])=[O:15]>>[F:1][C:2]1[CH:3]=[CH:4][C:5]([C:8]2[N:12]=[CH:13][C:14]([OH:15])=[N:16][CH:9]=2)=[CH:6][CH:7]=1

Participants

3

Reactant 2

HCID 69020GlycinamideHCID 101249(4-Fluorophenyl)glyoxal

Product 1

HCID 178516758HCID 178516758, compoundYield 42%

Procedure

The title compound was prepared according to the method described for Preparation 25 using (4-fluoro-phenyl)-oxo-acetaldehyde and 2-amino-acetamide to afford the title compound as a pale yellow oil (2.33 g, 42%).

Workup

  1. customThe title compound was prepared

Sources & evidence

ORD record
ord-8e7d716110824c19a262aede0f2ff9bf
Source dataset
uspto-grants-2012_10
Patent number
US08278343B2

Reaction notes

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