Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | Acrolein dimer | HCID 60994 | — |
| Reactant | 1H-Imidazole-1-propanamine | HCID 78736 | — |
| Reactant | HCID 12457675 | HCID 12457675 | — |
| Solvent | Ethanol | HCID 702 | — |
| Product | HCID 57924147 | HCID 57924147 | — |
Reaction Steps
3-Imidazol-1-yl-propylamine (1 mmol) and 3,4-Dihydro-2H-pyran-2-carbaldehyde (1 mmol) were added to ethanol (5 ml). After 30 min 3-(1H-Indol-3-yl)-2-oxo-propionic acid ethyl ester (1 mmol) was added. The reaction was heated to 50° C. and stirred for 24 h. After evaporation of the solvent the residue was purified with chromatographic methods.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| Patent number | US08278345B2 |
|---|
| Source dataset | uspto-grants-2012_10 |
|---|
| ORD ID | ord-6631e29c1e6049f8a4102a9b34e7e739 |
|---|
| Source note | uspto-grants-2012_10 |
|---|
