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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2060317Generated: October 27, 2026

5-Methylfurfural → 3-Hydroxy-1-(3-imidazol-1-yl-propyl)-5-(5-methyl-furan-2-yl)-4-pentyl-1,5-dihydro-pyrrol-2-one

https://huagongshe.com/reaction/2060317

Reaction equation

Participants

RoleNameHCIDCharge
Reactant5-MethylfurfuralHCID 12097—
Reactant1H-Imidazole-1-propanamineHCID 78736—
ReactantEthyl 2-oxooctanoateHCID 10888659—
SolventEthanolHCID 702—
Product3-Hydroxy-1-(3-imidazol-1-yl-propyl)-5-(5-methyl-furan-2-yl)-4-pentyl-1,5-dihydro-pyrrol-2-oneHCID 57923913—

Reaction Steps

3-Imidazol-1-yl-propylamine (1 mmol) and 5-Methyl-furan-2-carbaldehyde (1 mmol) were added to ethanol (5 ml). After 30 min 2-Oxo-octanoic acid ethyl ester (1 mmol) was added.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08278345B2
Source datasetuspto-grants-2012_10
ORD IDord-dff73c9e24e645e294aa4de5fefc730f
Source noteuspto-grants-2012_10