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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2060328Generated: November 1, 2026

2,1,3-Benzothiadiazole-5-carbaldehyde → HCID 178519910, compound

https://huagongshe.com/reaction/2060328

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2,1,3-Benzothiadiazole-5-carbaldehydeHCID 2776290—
ReactantEthyl 4-cyclopropyl-2,4-dioxobutanoateHCID 16779961—
ReactantHCID 178507353HCID 178507353—
SolventEthanolHCID 702—
ProductHCID 178519910HCID 178519910—

Reaction Conditions

Temperature50 °C

Reaction Steps

1H-Benzoimidazol-5-ylamine (1 mmol) and Benzo[1,2,5]thiadiazole-5-carbaldehyde (1 mmol) were added to ethanol (5 ml). After 30 min 4-Cyclopropyl-2,4-dioxo-butyric acid ethyl ester (1 mmol) was added. The reaction was heated to 50° C. and stirred for 24 h. After evaporation of the solvent the residue was purified with chromatographic methods.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08278345B2
Source datasetuspto-grants-2012_10
ORD IDord-16dcceae8bda4b3897834feb287dc9f5
Source noteuspto-grants-2012_10