HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2060329Generated: November 2, 2026
8-Hydroxy-2-quinolinecarboxaldehyde → HCID 178446986, compound
https://huagongshe.com/reaction/2060329
Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | 8-Hydroxy-2-quinolinecarboxaldehyde | HCID 599342 | — |
| Reactant | ethyl 6-methyl-2,4-dioxoheptanoate | HCID 3006751 | — |
| Reactant | HCID 178507353 | HCID 178507353 | — |
| Solvent | Ethanol | HCID 702 | — |
| Product | HCID 178446986 | HCID 178446986 | — |
Reaction Steps
1H-Benzoimidazol-5-ylamine (1 mmol) and 8-Hydroxy-quinoline-2-carbaldehyde (1 mmol) were added to ethanol (5 ml). After 30 min 6-Methyl-2,4-dioxo-heptanoic acid ethyl ester (1 mmol) was added. The reaction was heated to 50° C. and stirred for 24 h. After evaporation of the solvent the residue was purified with chromatographic methods.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
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| Patent number | US08278345B2 |
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| Source dataset | uspto-grants-2012_10 |
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| ORD ID | ord-39ce91dfa05f448e8b62668caaa33045 |
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| Source note | uspto-grants-2012_10 |
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