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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2060330Generated: November 1, 2026

5-Chloro-salicylaldehyde → HCID 178503662, compound

https://huagongshe.com/reaction/2060330

Reaction equation

Participants

RoleNameHCIDCharge
Reactant5-Chloro-salicylaldehydeHCID 12481—
Reactant4-Methylsulfanyl-2-oxo-butyric acid ethyl esterHCID 10241320—
ReactantHCID 178507353HCID 178507353—
SolventEthanolHCID 702—
ProductHCID 178503662HCID 178503662—

Reaction Conditions

Temperature50 °C

Reaction Steps

1H-Benzoimidazol-5-ylamine (1 mmol) and 5-Chloro2-Hydroxybenzaldehyde (1 mmol) were added to ethanol (5 ml). After 30 min 4-Methylsulfanyl-2-oxo-butyric acid ethyl ester (1 mmol) was added. The reaction was heated to 50° C. and stirred for 24 h. After evaporation of the solvent the residue was purified with chromatographic methods.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08278345B2
Source datasetuspto-grants-2012_10
ORD IDord-bbf27d6075834a9ab4bd2eb20032579e
Source noteuspto-grants-2012_10