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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2060337Generated: October 30, 2026

Benzo(c)(1,2,5)oxadiazole-5-carbaldehyde → HCID 178450346, compound

https://huagongshe.com/reaction/2060337

Reaction equation

Participants

RoleNameHCIDCharge
ReactantBenzo(c)(1,2,5)oxadiazole-5-carbaldehydeHCID 2776296—
ReactantEthyl 2,4-dioxoheptanoateHCID 3006750—
ReactantHCID 178507353HCID 178507353—
SolventEthanolHCID 702—
ProductHCID 178450346HCID 178450346—

Reaction Conditions

Temperature50 °C

Reaction Steps

1H-Benzoimidazol-5-ylamine (1 mmol) and Benzo[1,2,5]oxadiazole-5-carbaldehyde (1 mmol) were added to ethanol (5 ml). After 30 min 2,4-Dioxo-heptanoic acid ethyl ester (1 mmol) was added. The reaction was heated to 50° C. and stirred for 24 h. After evaporation of the solvent the residue was purified with chromatographic methods.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08278345B2
Source datasetuspto-grants-2012_10
ORD IDord-75f734811ca04cd6b2e7771c160718d9
Source noteuspto-grants-2012_10