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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2060341Generated: October 31, 2026

2,3,5-Trifluorobenzaldehyde → HCID 178516873, compound

https://huagongshe.com/reaction/2060341

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2,3,5-TrifluorobenzaldehydeHCID 2776950—
ReactantEthyl 2-oxo-3-phenylpropanoateHCID 12292599—
ReactantHCID 178507353HCID 178507353—
SolventEthanolHCID 702—
ProductHCID 178516873HCID 178516873—

Reaction Conditions

Temperature50 °C

Reaction Steps

1H-Benzoimidazol-5-ylamine (1 mmol) and 2,3,5 Trifluorobenzaldehyde (1 mmol) were added to ethanol (5 ml). After 30 min 2-Oxo-3-phenyl-propionic acid ethyl ester (1 mmol) was added. The reaction was heated to 50° C. and stirred for 24 h. After evaporation of the solvent the residue was purified with chromatographic methods.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08278345B2
Source datasetuspto-grants-2012_10
ORD IDord-c915636d2c4540ab9a872fe9ffecfdec
Source noteuspto-grants-2012_10