Potassium Hydroxide → Potassium 1-[(6-bromopyridin-2-yl)methyl]-1,2,3-triazole-4-carboxylate

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反応手順

To a solution of methyl 1-[(6-bromopyridin-2-yl)methyl]-1H-1,2,3-triazole-4-carboxylate (840 mg, 2.83 mmol) in tetrahydrofuran (6.0 mL) and methanol (3.0 mL) was added 1 M aqueous potassium hydroxide (3.11 mL, 3.11 mmol). The solution was stirred at room temperature for 3 h, during which time it became a white slurry. The solvent was evaporated to afford the title salt as a colorless solid that was carried forward without purification. LRMS (APCI) calc'd for C9H8BrN4O2 [M+H]+: 283, Found: 283.

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