Chloroform → HCID 68538466, compound

HRID 2060654Notes

Reaction equation

HRID 2060654 reaction equation
CC(O[CH2:5][C:6]1[C:11]2=[CH:12][CH:13]=[C:14](C=O)[C:10]2=COC=1)=O.[CH2:17]([NH2:35])[CH2:18][CH2:19][CH2:20][CH2:21][CH2:22][CH2:23][CH2:24][CH2:25][CH2:26][CH2:27][CH2:28][CH2:29][CH2:30][CH2:31][CH2:32][CH2:33][CH3:34].[CH:36](Cl)(Cl)Cl>>[CH2:18]([C:17]1[NH:35][CH:5]=[CH:6][C:11]2[C:10]=1[CH:14]=[CH:13][CH:12]=2)[CH2:19][CH2:20][CH2:21][CH2:22][CH2:23][CH2:24][CH2:25][CH2:26][CH2:27][CH2:28][CH2:29][CH2:30][CH2:31][CH2:32][CH2:33][CH2:34][CH3:36]

Participants

4

Reactant 3

HCID 6212ChloroformHCID 15793OctadecylamineHCID 159846Baldrinal2×

Product 1

HCID 68538466HCID 68538466, compound

Procedure

Baldrinal (2) (1.1 g) was reacted with octadecylamine (2.58 g) in 20 ml of chloroform. After stirring for 15 minutes at room temperature, the solution turned into thick red liquid. When all the baldrinal was reacted, an orange product (7) (53.4 mg) was collected after column chromatography on silica using 8:2 hexanes:ethyl acetate as a solvent.

Workup

  1. customan orange product (7) (53.4 mg) was collected after column chromatography on silica using 8:2 hexanes

Sources & evidence

ORD record
ord-da00dc4dad13490a84816bbc2254d5c5
Source dataset
uspto-grants-2012_10
Patent number
US08278451B2

Reaction notes

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