HuagongsheHuagongshe Chemistry Print Report · For research reference only
2-Cyclohexylethanamine hydrochloride → 4-{4-[(2-Cyclohexylethylamino)methyl]isoquinolin-1-yloxy}benzamide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2-Cyclohexylethanamine hydrochloride | HCID 200008 | — |
| Reactant | 4-(4-Formylisoquinolin-1-yloxy)benzamide | HCID 59401297 | — |
| Product | 4-{4-[(2-Cyclohexylethylamino)methyl]isoquinolin-1-yloxy}benzamide | HCID 25121478 | — |
Reaction Steps
Using the procedure outlined in Example 96, 4-(4-formylisoquinolin-1-yloxy)-benzamide (Preparation 16) and 2-cyclohexylethylamine hydrochloride were converted to the title compound: RT=2.70 min; m/z (ES+)=404.0 [M+H]+.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08278442B2 |
| Source dataset | uspto-grants-2012_10 |
| ORD ID | ord-0b9c711dc98a462f8d01a4c3c8288606 |
| Source note | uspto-grants-2012_10 |