Indole → HCID 59238985, compound

HRID 2060976Notes

Reaction equation

HRID 2060976 reaction equation
N1C2C(=CC=CC=2)C=C1.C([N:17]1[C:29]2[C:28]([OH:30])=[C:27]3[N:31](C(OC(C)(C)C)=O)[C:32]4[CH:33]=[CH:34][C:35]([Br:38])=[CH:36][C:37]=4[C:26]3=[CH:25][C:24]=2[C:23]2[C:18]1=[CH:19][CH:20]=[C:21]([Br:46])[CH:22]=2)(OC(C)(C)C)=O.[CH3:47][O:48][CH2:49][CH2:50][O:51][CH2:52][CH2:53]O>>[Br:38][C:35]1[CH:36]=[C:37]2[C:32](=[CH:33][CH:34]=1)[NH:31][C:27]1[C:28]([O:30][CH2:53][CH2:52][O:51][CH2:50][CH2:49][O:48][CH3:47])=[C:29]3[NH:17][C:18]4[CH:19]=[CH:20][C:21]([Br:46])=[CH:22][C:23]=4[C:24]3=[CH:25][C:26]2=1

Participants

4

Reactant 3

HCID 798IndoleHCID 8134Diethylene Glycol Monomethyl EtherHCID 16749420HCID 16749420, compound

Product 1

HCID 59238985HCID 59238985, compound

Procedure

The title compound was prepared in a manner analogous to Example 28 except the starting indole is 5,7-diBOC-2,10-dibromo-6-hydroxyindolo[2,3-b]carbazole and the reagent is diethylene glycol monomethyl ether. 1H-NMR (400 MHz, CDCl3) δ ppm 8.74 (s, 1H), 8.21 (d, J=2.0 Hz, 2H), 7.50-7.26 (m, 4H), 4.50-4.38 (m, 2H), 3.88-3.73 (m, 6H), 3.55 (s, 3H); MS (ESI) m/z 531.0 (M−H)−

Sources & evidence

ORD record
ord-9aab22870e8548ddbaaa0b2ab75e3a9c
Source dataset
uspto-grants-2012_10
Patent number
US08278341B2

Reaction notes

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