Indole → HCID 59238971, compound

HRID 2060991Notes

Reaction equation

HRID 2060991 reaction equation
[NH:1]1[C:9]2[C:4](=CC=CC=2)[CH:3]=[CH:2]1.Br[C:11]1[C:23]2[C:22]3[C:17](=[CH:18][CH:19]=[C:20]([Cl:24])[CH:21]=3)[NH:16][C:15]=2[C:14]([O:25][CH2:26][CH2:27][N:28]([CH3:30])[CH3:29])=[C:13]2[NH:31][C:32]3[CH:33]=[CH:34][C:35]([Cl:38])=[CH:36][C:37]=3[C:12]=12>>[Cl:38][C:35]1[CH:36]=[C:37]2[C:32](=[CH:33][CH:34]=1)[NH:31][C:13]1[C:14]([O:25][CH2:26][CH2:27][N:28]([CH3:30])[CH3:29])=[C:15]3[NH:16][C:17]4[CH:18]=[CH:19][C:20]([Cl:24])=[CH:21][C:22]=4[C:23]3=[C:11]([N:1]3[CH2:9][CH2:4][CH2:3][CH2:2]3)[C:12]2=1

Participants

3

Reactant 2

HCID 798IndoleHCID 59238960HCID 59238960, compound

Product 1

HCID 59238971HCID 59238971, compound

Procedure

The title compound was prepared in a manner analogous to Example 126 except the starting indole is 2-(12-bromo-2,10-dichloro-5,7-dihydroindolo[2,3-b]carbazol-6-yloxy)-N,N-dimethylethanamine. 1H-NMR (400 MHz, CDCl3) δ ppm 10.14 (br s, 2H), 8.11 (s, 2H), 7.37-7.28 (m, 4H), 4.34 (t, J=4.4 Hz, 2H), 3.67-3.55 (m, 4H), 2.72 (t, J=4.4 Hz, 2H), 2.53 (s, 6H), 2.45-2.33 (m, 4H); MS (ESI) m/z 479.1 (M−H)−; MS (ESI) m/z 481.1 (M+H)+

Sources & evidence

ORD record
ord-4c039a35d8da481e8086e33a8c6da8f6
Source dataset
uspto-grants-2012_10
Patent number
US08278341B2

Reaction notes

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