HCID 59205146, compound → HCID 59205147, compound

HRID 2061446Notes

Reaction equation

HRID 2061446 reaction equation
[N+:1]([C:4]1[CH:9]=[CH:8][CH:7]=[C:6]([O:10][CH2:11][C:12]([F:15])([F:14])[F:13])[C:5]=1[S:16]([NH2:19])(=[O:18])=[O:17])([O-])=O>CCO.[Pd]>[NH2:1][C:4]1[CH:9]=[CH:8][CH:7]=[C:6]([O:10][CH2:11][C:12]([F:14])([F:13])[F:15])[C:5]=1[S:16]([NH2:19])(=[O:18])=[O:17]

Participants

4

Reactant 1

HCID 59205146HCID 59205146, compound

Product 1

HCID 59205147HCID 59205147, compound

Reagents, catalysts & solvents 2

HCID 23938PalladiumCatalystHCID 702EthanolSolvent

Procedure

30 mg of 10% Pd on carbon are added to a solution of 2-nitro-6-(2,2,2-trifluoro-ethoxy)-benzenesulfonamide (63 mg, 0.21 mmol) in EtOH (10 mL). The mixture is stirred for 30 min under hydrogen. The catalyst is removed by filtration. Evaporation of solvent gives 2-amino-6-(2,2,2-trifluoro-ethoxy)-benzenesulfonamide.

Workup

  1. customThe catalyst is removed by filtration
  2. customEvaporation of solvent

Sources & evidence

ORD record
ord-f4305f5601154cbca46f0a9a0b0be780
Source dataset
uspto-grants-2012_10
Patent number
US08283356B2

Reaction notes

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