Hydrogen Bromide → HCID 22499224, compound

HRID 2061517Notes

Reaction equation

HRID 2061517 reaction equation
[BrH:1].[OH:2][C:3]1[CH:4]=[C:5]([CH3:14])[CH:6]=[C:7]2[C:12]=1[NH:11][C:10](=[O:13])[CH:9]=[CH:8]2>C(O)(=O)C.CS(C)=O>[Br:1][C:6]1[C:5]([CH3:14])=[CH:4][C:3]([OH:2])=[C:12]2[C:7]=1[CH:8]=[CH:9][C:10](=[O:13])[NH:11]2

Participants

5

Reactant 2

HCID 260Hydrogen BromideHCID 22499171HCID 22499171, compound

Product 1

HCID 22499224HCID 22499224, compound

Reagents, catalysts & solvents 2

HCID 176Acetic AcidSolventHCID 679Dimethyl SulfoxideSolvent

Procedure

A 45% solution of hydrobromic acid in acetic acid (324 μL) is added dropwise to a solution of 8-hydroxy-6-methyl-1H-quinolin-2-one (316 mg) in dimethylsulphoxide (9 mL) at room temperature. The reaction mixture is allowed to stand for 18 hours at room temperature and the solvent removed in vacuo.

Workup

  1. customthe solvent removed in vacuo

Sources & evidence

ORD record
ord-c5e7bd8ed6b549f6a8de3dd7809ef323
Source dataset
uspto-grants-2012_10
Patent number
US08283362B2

Reaction notes

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