反应详情

Prepared from 6-(2,2,2-trifluoroethoxy)pyridine-3-carboxylic acid (Apollo Scientific) and [(2-trifluoromethyl-1H-indol-5-yl)methyl]amine (Intermediate 4) according to the method as described of Compound 1; m/z (ES+) 418 (M+1); 1H NMR (400 MHz, d6-DMSO): δ 12.21 (1H, s), 9.16 (1H, t), 8.74 (1H, s), 8.27 (1H, dd), 7.62 (1H, s), 7.44 (1H, d), 7.30 (1H, dd), 7.08 (1H, dd), 7.00 (1H, s), 5.06 (2H, m), 4.57 (2H, d).