HuagongsheHuagongshe Chemistry Print Report · For research reference only
6-(2,2,2-Trifluoroethoxy)pyridine-3-carboxylic acid → HCID 58138933, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 6-(2,2,2-Trifluoroethoxy)pyridine-3-carboxylic acid | HCID 2781028 | — |
| Reactant | (2-(Trifluoromethyl)-1h-indol-5-yl)methanamine | HCID 58126817 | — |
| Reactant | HCID 58138928 | HCID 58138928 | — |
| Product | HCID 58138933 | HCID 58138933 | — |
Reaction Steps
Prepared from 6-(2,2,2-trifluoroethoxy)pyridine-3-carboxylic acid (Apollo Scientific) and [(2-trifluoromethyl-1H-indol-5-yl)methyl]amine (Intermediate 4) according to the method as described of Compound 1; m/z (ES+) 418 (M+1); 1H NMR (400 MHz, d6-DMSO): δ 12.21 (1H, s), 9.16 (1H, t), 8.74 (1H, s), 8.27 (1H, dd), 7.62 (1H, s), 7.44 (1H, d), 7.30 (1H, dd), 7.08 (1H, dd), 7.00 (1H, s), 5.06 (2H, m), 4.57 (2H, d).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08283365B2 |
| Source dataset | uspto-grants-2012_10 |
| ORD ID | ord-726926e063b34e3ba6bbacf1929ccfa8 |
| Source note | uspto-grants-2012_10 |