HuagongsheHuagongshe Chemistry Print Report · For research reference only
Tetrahydropyran-2-methanol → HCID 58010761, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Tetrahydropyran-2-methanol | HCID 7524 | — |
| Reactant | 1,1'-Carbonyldiimidazole | HCID 68263 | — |
| Solvent | Dichloromethane | HCID 6344 | — |
| Product | HCID 58010761 | HCID 58010761 | — |
Reaction Steps
A solution of (tetrahydro-2H-pyran-2-yl)methanol (1 g, 8.60 mmol) and di(1H-imidazol-1-yl)methanone (2.8 g, 17.2 mmol) in 17 mL CH2Cl2 was heated overnight at 50° C. The reaction was quenched with water, extracted with CH2Cl2, dried over MgSO4, filtered, and concentrated.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08283354B2 |
| Source dataset | uspto-grants-2012_10 |
| ORD ID | ord-17002067976344568fcfc93f1e14faef |
| Source note | uspto-grants-2012_10 |