Ammonia → 89032-88-2

HRID 2063152Notes

Reaction equation

HRID 2063152 reaction equation
[OH:1][C:2]1[N:3]=[N:4][C:5]([C:9]([OH:11])=O)=[C:6]([OH:8])[N:7]=1.[NH3:12]>CN(C)C=O>[O:1]=[C:2]1[NH:7][C:6](=[O:8])[C:5]([C:9]([NH2:12])=[O:11])=[N:4][NH:3]1

Participants

4

Reactant 2

HCID 222AmmoniaHCID 178524937HCID 178524937, compound

Product 1

HCID 1326667089032-88-2

Reagents, catalysts & solvents 1

HCID 6228DimethylformamideSolvent

Procedure

In 10 mL of dimethylformamide is suspended (0.5 g of 3,5-dihydroxy-1,2,4-triazine-6-carboxylic acid obtained according to the method described in literature (JP-A-54-79292). Then, 2.06 g of N,N′-carbonyldiimidazole is added thereto, and the resulting solution in stirred at ambient temperature for 6 hours. The reaction mixture is cooled with ice, saturated with gaseous ammonia, and then stirred for 15 minutes at the same temperature as above. The deposited crystals are collected by filtration to obtain 0.37 g of 3,5-dioxo-2,3,4,5-tetrahydro-1,2,4-triazine-6-carboxamide.

Workup

  1. customobtained
  2. stirringstirred for 15 minutes at the same temperature as above
  3. filtrationThe deposited crystals are collected by filtration

Sources & evidence

ORD record
ord-16a64fc71fdd447f84f1e636a4eb0102
Source dataset
uspto-grants-2012_10
Patent number
USRE043748E1

Reaction notes

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