Carbon tetrabromide → HCID 86597518, compound

HRID 2063237Notes

Reaction equation

HRID 2063237 reaction equation
[C:1]([C@:8]([NH2:17])([CH2:13][CH2:14][CH2:15]O)[C:9]([O:11][CH3:12])=[O:10])([O:3][C:4]([CH3:7])([CH3:6])[CH3:5])=[O:2].C1(P(C2C=CC=CC=2)C2C=CC=CC=2)C=CC=CC=1.C(Br)(Br)(Br)[Br:38]>>[C:1]([C@:8]([NH2:17])([CH2:13][CH2:14][CH2:15][Br:38])[C:9]([O:11][CH3:12])=[O:10])([O:3][C:4]([CH3:7])([CH3:6])[CH3:5])=[O:2]

Participants

4

Reactant 3

HCID 11205Carbon tetrabromideHCID 11776TriphenylphosphineHCID 86597519HCID 86597519, compound

Product 1

HCID 86597518HCID 86597518, compound

Procedure

The crude residue of methyl (S)2-BOC-amino-5-hydroxy-pentanoate is treated with triphenylphosphine and CBr4 to obtain a crude sample of methyl (S)2-BOC-amino-5-bromo-pentanoate.

Sources & evidence

ORD record
ord-399d420f50aa4a87958afd677bca1786
Source dataset
uspto-grants-2012_10
Patent number
US08288368B2

Reaction notes

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