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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2063241Generated: November 3, 2026

2-Methylthio-2-imidazoline hydroiodide → HCID 69234672, compound

https://huagongshe.com/reaction/2063241

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2-Methylthio-2-imidazoline hydroiodideHCID 88369—
ReactantHCID 69235497HCID 69235497—
ProductHCID 69234672HCID 69234672—

Reaction Steps

The (R)2-[(4-isobutylphenyl)-N-3-(aminopropyl)propionamide hydrochloride (see example 5) is converted in the free amine and treated with 2-methylthio-2-imidazoline iodohydrate (commercial reactant) according to the above cited Bodanszky procedure (J. Am. Chem. Soc., 86, 4452, 1964) to give (R)2-(4′-isobutylphenyl)-N-[3-(imidazolin-2-yl)aminopropyl]propionamide

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08288368B2
Source datasetuspto-grants-2012_10
ORD IDord-d9d9db9e6f4348e8889b2120646b0243
Source noteuspto-grants-2012_10