HuagongsheHuagongshe Chemistry Print Report · For research reference only
4-Hydroxymethylpyridine → HCID 66811885, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 4-Hydroxymethylpyridine | HCID 11472 | — |
| Reactant | Ethyl 5-(trifluoromethyl)-1H-pyrrolo[3,2-b]pyridine-2-carboxylate | HCID 66811603 | — |
| Product | HCID 66811885 | HCID 66811885 | 65.3% |
Reaction Steps
According to a process similar to that described in Example 24.1, using 5 g (18.4 mmol) of ethyl 5-tri-fluoromethyl-1H-pyrrolo[3,2-b]pyridine-2-carboxylate (Example 23.3) and 3.04 g (27.6 mmol) of (pyridin-4-yl)methanol, 4.2 g of the expected compound are isolated.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08288376B2 |
| Source dataset | uspto-grants-2012_10 |
| ORD ID | ord-38c5940ab7c04cabbd281ccb27895a63 |
| Source note | uspto-grants-2012_10 |