HuagongsheHuagongshe Chemistry Print Report · For research reference only
1-((4-methoxyphenyl)methyl)-1H-1,2,4-triazol-3-amine → 5-[1-(4-Methoxy-benzyl)-1H-[1,2,4]triazol-3-ylamino]-2-(4-methyl-imidazol-1-yl)-benzonitrile
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 1-((4-methoxyphenyl)methyl)-1H-1,2,4-triazol-3-amine | HCID 60911456 | — |
| Reactant | 5-bromo-2-(4-methyl-1H-imidazol-1-yl)benzonitrile | HCID 66961517 | — |
| Product | 5-[1-(4-Methoxy-benzyl)-1H-[1,2,4]triazol-3-ylamino]-2-(4-methyl-imidazol-1-yl)-benzonitrile | HCID 59324061 | — |
Reaction Steps
Prepared in analogy to example 1b) starting with 5-bromo-2-(4-methyl-imidazol-1-yl)-benzonitrile and 1-(4-methoxy-benzyl)-1H-[1,2,4]triazol-3-ylamine. The title compound was obtained as a colorless oil (Yield=34%). MS ISP (m/e): 386.2 (100) [(M+H)+].
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08288403B2 |
| Source dataset | uspto-grants-2012_10 |
| ORD ID | ord-d24ec868200146fe979963cb226c8846 |
| Source note | uspto-grants-2012_10 |