HuagongsheHuagongshe Chemistry Print Report · For research reference only
4-[(3-amino-1H-1,2,4-triazol-1-yl)methyl]benzonitrile → 5-[1-(4-Cyano-benzyl)-1H-[1,2,4]triazol-3-ylamino]-2-(4-methyl-imidazol-1-yl)-benzonitrile
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 4-[(3-amino-1H-1,2,4-triazol-1-yl)methyl]benzonitrile | HCID 60911729 | — |
| Reactant | 5-bromo-2-(4-methyl-1H-imidazol-1-yl)benzonitrile | HCID 66961517 | — |
| Product | 5-[1-(4-Cyano-benzyl)-1H-[1,2,4]triazol-3-ylamino]-2-(4-methyl-imidazol-1-yl)-benzonitrile | HCID 46216090 | — |
Reaction Steps
Prepared in analogy to example 1b) starting with 5-bromo-2-(4-methyl-imidazol-1-yl)-benzonitrile and 4-(3-amino-[1,2,4]triazol-1-ylmethyl)-benzonitrile. The title compound was obtained as an off-white solid (Yield=36%). MS ISP (m/e): 381.2 (100) [(M+H)+].
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08288403B2 |
| Source dataset | uspto-grants-2012_10 |
| ORD ID | ord-8c9e69b76d684b83b3bca0e56c331d78 |
| Source note | uspto-grants-2012_10 |