HuagongsheHuagongshe Chemistry Print Report · For research reference only
2-(Trifluoromethyl)aniline → 1-(2-trifluoromethyl-phenyl)-1H-[1,2,4]triazol-3-ylamine
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2-(Trifluoromethyl)aniline | HCID 6922 | — |
| Reactant | 5-Phenyl-1,2,4-oxadiazol-3-amine | HCID 2305446 | — |
| Product | 1-(2-trifluoromethyl-phenyl)-1H-[1,2,4]triazol-3-ylamine | HCID 62314005 | 94% |
Reaction Steps
Prepared in analogy to example 18a), starting with 5-phenyl-[1,2,4]oxadiazol-3-ylamine and 2-aminobenzotrifluoride. The title compound was obtained as brownish solid in a yield of 94%. MS ISP (m/e): 229.2 (64) [(M+H)+].
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08288403B2 |
| Source dataset | uspto-grants-2012_10 |
| ORD ID | ord-8bf32df4eb42479c8ab6b17b8ffe72e6 |
| Source note | uspto-grants-2012_10 |