HuagongsheHuagongshe Chemistry Print Report · For research reference only
5-bromo-2-(4-methyl-1H-imidazol-1-yl)benzonitrile → 2-(4-Methyl-imidazol-1-yl)-5-[1-(3,4,5-trifluoro-benzyl)-1H-pyrazol-3-ylamino]-benzonitrile
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 5-bromo-2-(4-methyl-1H-imidazol-1-yl)benzonitrile | HCID 66961517 | — |
| Reactant | 1-(3,4,5-Trifluoro-benzyl)-1H-pyrazol-3-ylamine | HCID 67342971 | — |
| Product | 2-(4-Methyl-imidazol-1-yl)-5-[1-(3,4,5-trifluoro-benzyl)-1H-pyrazol-3-ylamino]-benzonitrile | HCID 46216600 | — |
Reaction Steps
Prepared in analogy to example 1b) starting with 5-bromo-2-(4-methyl-imidazol-1-yl)-benzonitrile and 1-(3,4,5-trifluoro-benzyl)-1H-pyrazol-3-ylamine. The title compound was obtained as a white solid (Yield=56%). MS ISP (m/e): 409.3 (100) [(M+H)+].
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08288403B2 |
| Source dataset | uspto-grants-2012_10 |
| ORD ID | ord-0612cbe31e29465b90634b557c641e36 |
| Source note | uspto-grants-2012_10 |