HuagongsheHuagongshe Chemistry Print Report · For research reference only
1-(4-bromo-2-methoxyphenyl)-4-methyl-1H-imidazole → [3-Methoxy-4-(4-methyl-imidazol-1-yl)-phenyl]-[1-(3,4,5-trifluoro-benzyl)-1H-[1,2,4]triazol-3-yl]-amine
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 1-(4-bromo-2-methoxyphenyl)-4-methyl-1H-imidazole | HCID 53415661 | — |
| Reactant | HCID 67343001 | HCID 67343001 | — |
| Product | [3-Methoxy-4-(4-methyl-imidazol-1-yl)-phenyl]-[1-(3,4,5-trifluoro-benzyl)-1H-[1,2,4]triazol-3-yl]-amine | HCID 46216605 | — |
Reaction Steps
Prepared in analogy to example 1b) starting with 1-(4-bromo-2-methoxy-phenyl)-4-methyl-1H-imidazole (WO2009076352) and 1-(3,4,5-trifluoro-benzyl)-1H-[1,2,4]triazol-3-ylamine from example 17a). The title compound was obtained as a colorless foam (Yield=49%). MS ISP (m/e): 415.2 (100) [(M+H)+].
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08288403B2 |
| Source dataset | uspto-grants-2012_10 |
| ORD ID | ord-a836b534da554deabef8bea8b67b6c29 |
| Source note | uspto-grants-2012_10 |