Hydrochloric Acid → HCID 69812088, compound

HRID 2063716Notes

Reaction equation

HRID 2063716 reaction equation
[ClH:1].[CH3:2][N:3]([CH3:25])[C:4]1([C:19]2[CH:24]=[CH:23][CH:22]=[CH:21][CH:20]=2)[CH2:9][CH2:8][CH:7]([CH:10]([OH:18])[CH2:11][C:12]2[CH:17]=[CH:16][CH:15]=[CH:14][CH:13]=2)[CH2:6][CH2:5]1>C(OCC)C>[ClH:1].[CH3:25][N:3]([CH3:2])[C:4]1([C:19]2[CH:24]=[CH:23][CH:22]=[CH:21][CH:20]=2)[CH2:9][CH2:8][CH:7]([CH:10]([OH:18])[CH2:11][C:12]2[CH:17]=[CH:16][CH:15]=[CH:14][CH:13]=2)[CH2:6][CH2:5]1

Participants

4

Reactant 2

HCID 313Hydrochloric AcidHCID 44224238HCID 44224238, compound

Product 1

HCID 69812088HCID 69812088, compound

Reagents, catalysts & solvents 1

HCID 3283Diethyl EtherSolvent

Procedure

A 7.5 M solution of hydrogen chloride in diethyl ether (25 ml) was added to 1-(4-dimethylamino-4-phenylcyclohexyl)-2-phenylethanol (nonpolar Diastereoisomer, 140 mg, 0.41 mmol). The supernatant solution was decanted and the precipitate was dried over potassium hydroxide i. vac. in a desiccator.

Workup

  1. customThe supernatant solution was decanted
  2. dry with materialthe precipitate was dried over potassium hydroxide i

Sources & evidence

ORD record
ord-1c8ff76a1a1f40caa03a89abba481684
Source dataset
uspto-grants-2012_10
Patent number
US08288406B2

Reaction notes

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