Dichloromethane → Trifluoroacetic acid

HRID 206453Notes

Reaction equation

HRID 206453 reaction equation
[CH:1]1([CH:6]([CH2:7][CH:8]=[C:9]([F:10])[F:11])[n:12]2[n:13][cH:14][c:15](-[c:17]3[c:18]4[c:19]([n:20][cH:21][n:22]3)[n:23]([CH2:26][O:27][CH2:28][CH2:29][Si:30]([CH3:31])([CH3:32])[CH3:33])[cH:24][cH:25]4)[cH:16]2)[CH2:2][CH2:3][CH2:4][CH2:5]1.[Cl:41][CH2:42][Cl:43].[F:34][C:35]([C:36](=[O:37])[OH:38])([F:39])[F:40]>>[CH:1]1([CH:6]([CH2:7][CH:8]=[C:9]([F:10])[F:11])[n:12]2[n:13][cH:14][c:15](-[c:17]3[c:18]4[c:19]([n:20][cH:21][n:22]3)[nH:23][cH:24][cH:25]4)[cH:16]2)[CH2:2][CH2:3][CH2:4][CH2:5]1.[F:34][C:35]([C:36](=[O:37])[OH:38])([F:39])[F:40]

Participants

5

Reactant 3

HCID 6344DichloromethaneHCID 6422Trifluoroacetic acidHCID 574780384-[1-(1-cyclopentyl-4,4-difluorobut-3-en-1-yl)-1H-pyrazol-4-yl]-7-[2-(trimethylsilyl)ethoxy]methyl-7H-pyrrolo[2,3-d]pyrimidine

Product 2

HCID 6422Trifluoroacetic acidHCID 57478011HCID 57478011, compound

Sources & evidence

ORD record
ord-917061123a5346c08eebb9832f94f180
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (6/10)

Reaction notes

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