Methylamine → HCID 178485284, compound

HRID 2064574Notes

Reaction equation

HRID 2064574 reaction equation
[NH:1]1[C:9]2[C:4](=[CH:5][CH:6]=[CH:7][CH:8]=2)[C:3]([C:10]2[NH:14][C:13]3[CH:15]=[CH:16][C:17]([C:19]([OH:21])=O)=[CH:18][C:12]=3[N:11]=2)=[N:2]1.[CH3:22][NH2:23]>>[CH3:22][NH:23][C:19]([C:17]1[CH:16]=[CH:15][C:13]2[NH:14][C:10]([C:3]3[C:4]4[C:9](=[CH:8][CH:7]=[CH:6][CH:5]=4)[NH:1][N:2]=3)=[N:11][C:12]=2[CH:18]=1)=[O:21]

Participants

3

Reactant 2

HCID 6329MethylamineHCID 178524162HCID 178524162, compound

Product 1

HCID 178485284HCID 178485284, compound

Procedure

Starting with 20 mg of 2-(1H-indazol-3-yl)-1H-benzimidazole-5-carboxylic acid and 71.8 μl of a methylamine solution (2M in tetrahydrofuran), 14.8 mg of expected product are obtained.

Sources & evidence

ORD record
ord-2cd74ca4830742d98986f78cb99101c0
Source dataset
uspto-grants-2012_10
Patent number
US08288425B2

Reaction notes

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