反应详情

A stirred solution of semicarbazide hydrochloride (11.1 g) and sodium acetate (8.2 g) in water (250 ml) was treated with ethyl pyruvate (10.9 ml) in one portion. The resulting white precipitate was collected by filtration to yield ethyl pyruvate semicarbazide (16.59 g) as a white powder. LC-MS (Method J): RT=2.38 minutes, 174.31 (M+H)+, 172.32 (M−H)−.

1. filtrationThe resulting white precipitate was collected by filtration