反应详情

温度

60 °C

To a stirred solution of chlorosulfonic acid (20 ml) at 0° C., was added N-phenylurethane (9.90 g) at such a rate that the temperature did not exceed 20° C. The reaction was then heated at 60° C. for 3 hours, cooled to ambient temperature and poured carefully onto ice. The resultant precipitate was collected by filtration and dried in vacuo to give (4-chlorosulfonyl-phenyl)-carbamic acid ethyl ester (140.50 g) as an off-white solid. LC-MS (METHOD B): RT=3.11 minutes, 284.23 (M+H)+.

1. customdid not exceed 20° C
2. temperaturecooled to ambient temperature
3. additionpoured carefully onto ice
4. filtrationThe resultant precipitate was collected by filtration
5. customdried in vacuo