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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2064698Generated: October 30, 2026

Thioacetamide → 5-(3-Fluoro-phenyl)-2-methyl-thiazole-4-carboxylic acid methyl ester

https://huagongshe.com/reaction/2064698

Reaction equation

Participants

RoleNameHCIDCharge
ReactantThioacetamideHCID 2723949—
ReactantMethyl 3-chloro-3-(3-fluorophenyl)-2-oxopropanoateHCID 57437155—
Product5-(3-Fluoro-phenyl)-2-methyl-thiazole-4-carboxylic acid methyl esterHCID 57437164—

Reaction Steps

prepared by reaction of 3-chloro-3-(3-fluoro-phenyl)-2-oxo-propionic acid methyl ester with thioacetamide. LC-MS: tR=0.91 min; [M+H]+=252.1.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08288435B2
Source datasetuspto-grants-2012_10
ORD IDord-fcc52418e71440aea30dbd04f970bd12
Source noteuspto-grants-2012_10