HuagongsheHuagongshe Chemistry Print Report · For research reference only
Thioacetamide → 2-Methyl-5-(3,4-difluoro-phenyl)-thiazole-4-carboxylic acid methyl ester
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Thioacetamide | HCID 2723949 | — |
| Reactant | 3-Chloro-3-(3,4-difluoro-phenyl)-2-oxo-propionic acid methyl ester | HCID 64900454 | — |
| Product | 2-Methyl-5-(3,4-difluoro-phenyl)-thiazole-4-carboxylic acid methyl ester | HCID 66703730 | — |
Reaction Steps
prepared by reaction of 3-chloro-3-(3,4-difluoro-phenyl)-2-oxo-propionic acid methyl ester with thioacetamide. LC-MS: tR=0.92 min; [M+H]+=270.3.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08288435B2 |
| Source dataset | uspto-grants-2012_10 |
| ORD ID | ord-ae22dea99c07432e97e762dd1c33e2fe |
| Source note | uspto-grants-2012_10 |