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HRID2064794

反应详情

EQUATION

反应方程式

HRID 2064794 的结构方程式

REACTANTS

反应物

2
结构：Cc1nc2sccn2c1C(=O)O
HCID329979

6-METHYLIMIDAZO[2,1-B][1,3]THIAZOLE-5-CARBOXYLIC ACID

C7H6N2O2S

结构：CC(C)(C)OC(=O)N1[C@H](CN)C[C@@H]2C[C@@H]21
HCID58278675

未命名化合物

PRODUCTS

生成物

1
结构：Cc1nc2sccn2c1C(=O)NC[C@@H]1C[C@@H]2C[C@@H]2N1C(=O)OC(C)(C)C
HCID67080943

未命名化合物

PROCEDURE

实验过程

prepared by reaction of (1S,3S,5S)-3-aminomethyl-2-aza-bicyclo[3.1.0]hexane-2-carboxylic acid tert-butyl ester with 6-methyl-imidazo[2,1-b]thiazole-5-carboxylic acid. LC-MS (acidic): tR=0.84 min; [M+H]+=377.1. 1H-NMR (CDCl3): δ=0.54 (bs, 1H); 0.80-0.86 (m, 1H); 1.50 (s, 9H); 1.51-1.58 (m, 1H); 1.77 (bd, J=11.8 Hz, 1H); 2.53-2.61 (m, 1H); 2.68 (s, 3H); 3.17-3.24 (m, 1H); 3.59-3.69 (m, 2H); 4.39-4.45 (m, 1H); 6.84 (d, J=4.3 Hz, 1H); 7.79 (bs, 1H); 8.27 (d, J=4.4, 1H).