HuagongsheHuagongshe Chemistry Print Report · For research reference only
2-(3-chlorophenyl)benzoic Acid → 2,3-dihydro-benzo[1,4]dioxine-5-carboxylic acid [(1S,3S,5S)-2-(3'-chloro-biphenyl-2-carbonyl)-2-aza-bicyclo[3.1.0]hex-3-ylmethyl]-amide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2-(3-chlorophenyl)benzoic Acid | HCID 2757415 | — |
| Reactant | 2,3-dihydro-benzo[1,4]dioxine-5-carboxylic acid [(1S,3S,5S)-2-aza-bicyclo[3.1.0]hex-3-ylmethyl]-amide | HCID 67081414 | — |
| Product | 2,3-dihydro-benzo[1,4]dioxine-5-carboxylic acid [(1S,3S,5S)-2-(3'-chloro-biphenyl-2-carbonyl)-2-aza-bicyclo[3.1.0]hex-3-ylmethyl]-amide | HCID 67081325 | — |
Reaction Steps
prepared by reaction of 2,3-dihydro-benzo[1,4]dioxine-5-carboxylic acid [(1S,3S,5S)-2-aza-bicyclo[3.1.0]hex-3-ylmethyl]-amide with 3′-chloro-biphenyl-2-carboxylic acid. LC-MS (basic): tR=1.43 min; [M+H]+=489.0.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08288435B2 |
| Source dataset | uspto-grants-2012_10 |
| ORD ID | ord-4345ae7d13a24467853b4c119c77a578 |
| Source note | uspto-grants-2012_10 |