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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2065168Generated: October 26, 2026

3-(Trifluoromethoxy)cinnamic Acid → (E)-N-[1-(5-Oxo-hexyl)-1H-pyrazol-4-yl]-3-(3-trifluoromethoxy-phenyl)-acrylamide

https://huagongshe.com/reaction/2065168

Reaction equation

Participants

RoleNameHCIDCharge
Reactant3-(Trifluoromethoxy)cinnamic AcidHCID 735840—
Reactant1-[4-(2-Methyl-[1,3]dioxolan-2-yl)-butyl]-1H-pyrazol-4-ylamineHCID 66928726—
Product(E)-N-[1-(5-Oxo-hexyl)-1H-pyrazol-4-yl]-3-(3-trifluoromethoxy-phenyl)-acrylamideHCID 66929327—

Reaction Steps

Following general procedure B followed by either C or D, starting from 1-[4-(2-methyl-[1,3]dioxolan-2-yl)-butyl]-1H-pyrazol-4-ylamine and (E)-3-(3-trifluoromethoxy-phenyl)-acrylic acid.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08288419B2
Source datasetuspto-grants-2012_10
ORD IDord-d86a342de7604aad88b33f9fdcd1a69e
Source noteuspto-grants-2012_10